Table 2.

Frequency distribution of haplotypes and alleles of APOE.

	Control group (N = 183)	AD group (N = 136)
APOE haplotypes
ε2/ε2	2 (1.1%)	—
ε2/ε3	31 (16.9%)	10 (7.4%)
ε3/ε3	111 (60.7%)	64 (47.1%)
ε2/ε4	9 (4.9%)	4 (2.9%)
ε3/ε4	28 (15.3%)	44 (32.4%)a
ε4/ε4	2 (1.1%)	14 (10.3%)a
Allele frequencies
ε2	0.12	0.07
ε3	0.77	0.47a
ε4	0.11	0.46a

^a P value < 0.01 compared between controls and AD groups.