Table 6.
Unique glycoproteins in the AD group classified by the molecular function, biological process, and pathways.
| Classification | Percentage (%) | Classification | Percentage (%) |
|---|---|---|---|
| Molecular function | Pathways | ||
| Organic cyclic compound binding (GO:0097159) | 26.0 | Alzheimer disease-presenilin pathway (P00004) | 16.60% |
| Heterocyclic compound binding (GO:1901363) | 26.0 | Inflammation mediated by chemokine and cytokine signaling pathway (P00031) | 9.20% |
| Protein binding (GO:0005515) | 24.7 | Apoptosis signaling pathway (P00006) | 5.10% |
| Ion binding (GO:0043167) | 5.5 | Integrin signaling pathway (P00034) | 5.10% |
| Small molecule binding (GO:0036094) | 5.5 | Wnt signaling pathway (P00057) | 5.10% |
| Carbohydrate binding (GO:0030246) | 5.6 | p53 pathway (P00059) | 3.70% |
| Carbohydrate derivative binding (GO:0097367) | 4.1 | Metabotropic glutamate receptor group III pathway (P00039) | 2.60% |
| Protein-containing complex binding (GO:0044877) | 2.7 | Ionotropic glutamate receptor pathway (P00037) | 2.60% |
| Biological process | Gamma-aminobutyric acid synthesis (P04384) | 2.60% | |
| Cellular process (GO:0009987) | 32.30% | Dopamine receptor-mediated signaling pathway (P05912) | 2.60% |
| Metabolic process (GO:0008152) | 15.50% | p53 pathway feedback loops 2 (P04398) | 2.60% |
| Biological regulation (GO:0065007) | 15.10% | Endothelin signaling pathway (P00019) | 2.60% |
| Response to stimulus (GO:0050896) | 9.20% | Parkinson disease (P00049) | 2.60% |
| Localization (GO:0051179) | 8.00% | EGF receptor signaling pathway (P00018) | 2.60% |
| Signaling (GO:0023052) | 6.40% | PDGF signaling pathway (P00047) | 2.60% |
| Developmental process (GO:0032502) | 4.80% | Ras pathway (P04393) | 2.60% |
| Multicellular organismal process (GO:0032501) | 4.80% | Notch signaling pathway (P00045) | 2.60% |
| Others | 4.0% | Muscarinic acetylcholine receptor 2 and 4 signaling pathway (P00043) | 2.60% |
| Cadherin signaling pathway (P00012) | 2.60% | ||
| Metabotropic glutamate receptor group I pathway (P00041) | 2.60% | ||
| Carbohydrate derivative binding (GO:0097367) | 4.1 | Metabotropic glutamate receptor group II pathway (P00040) | 2.60% |
| CCKR signaling map (P06959) | 2.60% | ||
| Beta2 adrenergic receptor signaling pathway (P04378) | 2.60% | ||
| Formyltetrahydroformate biosynthesis (P02743) | 2.60% | ||
| Beta1 adrenergic receptor signaling pathway (P04377) | 2.60% | ||
| 5HT1 type receptor-mediated signaling pathway (P04373) | 2.60% | ||
| Transcription regulation by bZIP transcription factor (P00055) | 2.60% | ||
| GABA-B receptor II signaling (P05731) | 2.60% | ||
| Enkephalin release (P05913) | 1.50% | ||
| B cell activation (P00010) | 1.00% |