Table 7.
Soft tissue healing outcomes in the evaluated studies
| Study | n | Test | Control | Method | Results test | Results control | Statistics |
|---|---|---|---|---|---|---|---|
| Sharma et al. [54] | 30 | PRF | Spontaneous healing | The Landry wound healing index (mean ± SD) |
Day 3: 3.43 ± 0.504 Day 7: 3.93 ± 0.254 Day 14: 4.83 ± 0.379 |
Day 3: 3.17 ± 0.379 Day 7: 3.73 ± 0.082 Day 14: 4.3 ± 0.46 |
Day 3: yes p = 0.025 Day 7: yes P = 0.039 Day 14: yes p = 0.00 |
| Mourao et al. [56] | 32 | L-PRF | Spontaneous healing | Wound healing index (mean ± SD) |
Week 1: 3.81 ± 0.65 Week 2: 4.75 ± 0.44 |
Week 1: 3.18 ± 0.54 Week 2: 4.5 ± 0.51 |
Week 1: Yes p = 0.0138 Week 2: No |
| Srinivas et al. [48] | 30 | PRF | Spontaneous healing | Wound healing index after 7 days | 3.8 ± 0.40 | 3.0 ± 0.53 |
Yes P < 0.001 |
| Ahmed et al. [53] | Spontaneous healing | Wound healing index | Very good 94.1% | Very good in 86.7% | Not reported | ||
| Ustaoglu et al. [42] | 57 | L-PRF | Spontaneous healing | The Landry wound healing index (mean ± SD) |
Week 1: 3.58 ± 0.63 Week 2: 4.59 ± 0.51 |
Week 1: 3.21 ± 0.66 Week 2: 4.38 ± 0.49 |
Week 1: no Week 2: no |
| Spontaneous healing | Complete wound epithelization (%) |
Week 1: 54.9 Week 2: 100 |
Week 1: 10.1 Week 2: 40.7 |
Week 1: yes P = 0.047 Week 2: yes P = 0.041 |
|||
| T-PRF | Spontaneous healing | The Landry wound healing index (mean ± SD) |
Week 1: 3.69 ± 0.51 Week 2: 4.71 ± 0.50 |
Week 1: 3.21 ± 0.66 Week 2: 4.38 ± 0.49 |
Week 1: no Week 2: no |
||
| Spontaneous healing | Complete wound epithelization (%) |
Week 1: 70.1 Week 2: 100 |
Week 1: 10.1 Week 2: 40.7 |
Week 1: yes P = 0.047 Week 2: yes P = 0.041 |
|||
| Giudice et al. [40] | 40 | A-PRF + | Spontaneous healing | Wound healing index (mean) |
Week 1: 1 Week 2: 0.25 |
Week 1: 1.05 Week 2: 0.33 |
No |
| L-PRF | Spontaneous healing | Wound healing index (mean) |
Week 1: 0.95 Week 2: 0.15 |
Week 1: 1.05 Week 2: 0.33 |
No | ||
| Asmael et al. [58] | 20 | PRF | Spontaneous healing | Percentage of epithelization after 1 week | 52.7% | 51.3% | No |
| The Landry wound healing index (mean) after 1 week | 3.45 | 4.2 |
Yes P = 0.0035 |
||||
|
15 Marenzi et al. [57] |
L-PRF | Spontaneous healing | Wound healing index (mean ± SD) |
Day 3: 4.8 ± 0.6 Day 7: 4.5 ± 0.5 Day 14: 4.2 ± 0.2 Day 21: 4.1 ± 0.1 |
Day 3: 5.1 ± 0.9 Day 7: 4.9 ± 0.3 Day 14: 4.3 ± 0.3 Day 21: 4.2 ± 0.2 |
Day 3: No p = 0.197 Day 7: yes p = 0.05 Day 14: yes p = 0.01 Day 21: yes p = 0.0002 |