Table 4.
Studies classified by pCR-definition
| pCR-definition/first author | pCR rate (95% CI) | Na | Totalb |
|---|---|---|---|
| No invasive. No DCIS | |||
| Santamaria [27] | 0.19 (0.12–0.26) | 21 | 111 |
| Minarikova (baseline) [59] | 0.17 (0.05–0.28) | 7 | 42 |
| Minarikova (after 5 cycles) [59] | 0.15 (0.03–0.27) | 5 | 33 |
| Woodhams [64]c | 0.13 (0.05–0.21) | 9 | 70 |
| No invasive. DCIS may be present | |||
| Che [19] | 0.19 (0.07–0.32) | 7 | 36 |
| Bedair [20] | 0.39 (0.23–0.55) | 14 | 36 |
| Fangberget [65] | 0.37 (0.19–0.54) | 11 | 30 |
| Shin [26] | 0.37 (0.22–0.51) | 15 | 41 |
| Hahn [67] | 0.24 (0.15–0.34) | 19 | 78 |
| Yuan [22] | 0.28 (0.21–0.36) | 40 | 142 |
| Partridge (pre) [23] | 0.31 (0.25–0.37) | 71 | 227 |
| Partridge (mid) [23] | 0.33 (0.27–0.40) | 70 | 210 |
| Partridge (post) [23] | 0.34 (0.27–0.41) | 63 | 186 |
| Gallivanone [21]d | 0.42 (0.25–0.59) | 13 | 31 |
| Fujimoto [66] | 0.14 (0.05–0.23) | 8 | 56 |
| Woodhams [64]e | 0.13 (0.23–0.33) | 16 | 70 |
| Pereira [18] | 0.39 (0.27–0.51) | 24 | 62 |
| No invasive (without specification) | |||
| Bufi [17] | 0.17 (0.12–0.22) | 39 | 225 |
| Ramirez-Galván [25]f | 0.25 (0.04–0.46) | 4 | 16 |
| Li [44] | 0.33 (0.19–0.48) | 14 | 42 |
| Near pCR | |||
| Liu [16]g | 0.18 (0.12–0.24) | 32 | 176 |
| Kim [53]g | 0.30 (0.17–0.44) | 14 (5: real pCR) | 46 |
| No definition for pCR | |||
| Tozaki [40] | 0.14 (0–0.40) | 1 | 7 |
pCR pathologic complete response, DCIS ductal carcinoma in situ, CI confidence interval
aLesions/patients with a pCR
bTotal lesions/patients
cData extracted from supplementary material
dCalculated from 42% pCR from full-text
eBroader pCR-definition including DCIS, in addition to original pCR-definition in full-text. Data extracted by supplementary materials
fMiller and Payne grade 5
gMiller and Payne 4 included, in Kim et al. [53] was labeled as good responders