Table 1.
Characteristics of the included studies
| Study | Year | Region | Tumor type | Sample size (low/high) | HR (95% CI) | Outcome | Method | Follow-up months | NOS |
|---|---|---|---|---|---|---|---|---|---|
| Li [18] | 2020 | China | NSCLC | 63 (31/32) | 0.44 (0.23, 0.84) | OS | qRT-PCR | 60 | 7 |
| Yang [13] | 2019 | China | CRC | 135 (43/92) | 0.36 (0.16, 0.81) | CP, OS | qRT-PCR | 60 | 7 |
| Zhao [26] | 2019 | China | OSCC | 73 (37/36) | 0.63 (0.35, 1.13) | CP, OS | qRT-PCR | 60 | 7 |
| Hao [19] | 2020 | China | ccRCC | 66 (33/33) | 0.55 (0.28, 1.08) | CP, OS | qRT-PCR | 60 | 7 |
| Liang [17] | 2021 | China | GC | 36 (18/18) | 0.47 (0.24, 0.92) | OS | qRT-PCR | 60 | 6 |
| Qin [16] | 2021 | China | GC | 98 (49/49) | 0.36 (0.13, 1.00) | CP, OS | qRT-PCR | 36 | 6 |
| Zhang [27] | 2020 | China | ccRCC | 76 (38/38) | 0.33 (0.09, 1.19) | OS | qRT-PCR | 60 | 7 |
| Tu [20] | 2021 | China | OSC | 40 (21/19) | 0.33 (0.09, 1.21) | OS | qRT-PCR | 60 | 6 |
| Wei [15] | 2019 | China | SKCM | 54 (27/27) | 2.97 (1.64, 5.36) | CP, OS | qRT-PCR | 105 | 7 |
NSCLC non-small cell lung cancer, CRC colorectal cancer, OSCC Oral squamous cell carcinoma, ccRCC clear cell renal cell carcinoma, GC gastric cancer, SKCM skin cutaneous melanoma, OSC osteosarcoma, CP clinicopathological parameters, OS overall survival, HR hazard ratios, CI confidence intervals, NA not available, NOS Newcastle–Ottawa Scale