FIGURE 4:

Polarity factors that alter the growth pattern or cell morphology of rga4∆ cells. SGA screen to identify factors that alter the growth pattern of rga4∆ cells. Loss of the Cdc42 GEF Gef1 and the DRCK kinase Pom1 suppress aspects of the rga4∆ phenotype. Loss of the Cdc42-negative regulators, the GDI Rdi1, and the Cdc42 GAP Rga6 worsen the morphology of rga4∆ bipolar cells. The functional genetic interactions of rga4 with rga6 and ypa2/pta2 have been previously published (Bernal et al., 2012; Revilla-Guarinos et al., 2016).