Fig. 4. Expression of HMGB1 and RAGE in lung tissues of individuals from each of the three groups assessed. (A) Expression of HMGB1 and (B) RAGE in the (a) model, (b) therapy, and (c) control group compared with the model group (*P <0.05). HMGB1: high mobility group protein B1; RAGE: receptor for advanced glycation end-product.