FIGURE 6.
Pyridoxamine (PM) improves the impairment of M1 macrophages phagocytosis induced by methylglyoxal (MGO). Cells were treated with MGO (10 μM, using H2O as control) for 24 hours. M1 macrophages were treated with MGO (10 μM) or MGO (10 μM) + PM (100 μM), using H2O as control, for 24 hours. A‐C, Representative results of phagocytosis percentage. D‐F, Phagocytosis percentage was analysed by flow cytometry. **P < .01 compared with the control group. n = 3. G, Representative images of phagocytosis percentage. H, Phagocytosis percentage was analysed by flow cytometry. *P < .05 compared with the control group. ##P < .01 compared with the MGO group. n = 4