FIGURE 7.

Topical application of pyridoxamine (PM) alleviates excessive inflammation in diabetic wounds. WT‐NS (normal saline‐treated wild‐type control mice). db/db‐NS (normal saline‐treated diabetic control mice). db/db‐PM (pyridoxamine‐treated diabetic experimental mice). Mice wounds tissue was collected on days 3, 7, and 10 post‐wounding of each group. A‐E, The concentrations of TNF‐α, IFN‐γ, IL‐6, IL‐12, and IL‐10 of each group were quantified by enzyme‐linked immunosorbent assay. F, IL12/IL10. *P < .05, **P < .01 compared with the WT‐NS group. #P < .05, ##P < .01 compared with the db/db‐NS group. n = 3