FIGURE 1.

Multiple Layers of Regulation on Plant Leaf Senescence. Plant leaf senescence is finely regulated by endogenous developmental signals, and external environmental cues in an age-dependent manner. The multiple layers of regulation on leaf senescence includes epigenetic regulation at the chromatin level involved in histone proteases, DNA methylation modifying enzymes and chromatin remodeling factors, the master transcription factors involved in transcription regulation such as WRKYs and NACs, also includes miRNA and alternative splicing involved in the post-transcriptional level, and translation initiation and elongation factors involved in the regulation of translation level, as well as post-translational ubiquitination and phosphorylation. SAP, senescence-associated protein; Ub, ubiquitin; TF, transcription factors.