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. 2021 Dec 6;12:784110. doi: 10.3389/fimmu.2021.784110

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Copyright © 2021 Teniente-Serra, Pizarro, Quirant-Sánchez, Fernández, Vives-Pi and Martinez-Caceres

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in lymphocyte subpopulations at established disease when compared with onset. A subgroup of patients (n=6) was followed-up at established disease (>2 years of evolution) and compared their own timepoint onset of the disease. Percentage and counts of CD3 (A, B), counts of CD4 and CD8 T cells (C, D), percentage and counts of Th17 cells (E, F), percentage and counts of immature B cells (G, H) and percentage of IgM-only memory B cells (I) at onset and long-course are represented for each patient. LC, long-course. (p < 0.05 significative; Mann-Whitney test).