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. 2021 Dec 6;11:793025. doi: 10.3389/fonc.2021.793025

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Copyright © 2021 Ren, Sun, Li, Zhang, Yang and Cao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of MK3 expression with PD-1, PD-L1, and CTLA-4 in glioma. (A–C) Correlation of MK3 expression with PD-1 (A), PD-L1 (B), and CTLA-4 (C) in GBM adjusted by tumor purity using TIMER. (D–F) Correlation of MK3 expression with PD-1 (D), PD-L1 (E), and CTLA-4 (F) in LGG adjusted by tumor purity using TIMER. (G–I) The expression correlation of MK3 with PD-1 (G), PD-L1 (H), and CTLA-4 (I) in GBM and LGG samples from TCGA dataset. GBM, glioblastoma; TIMER, Tumor IMmune Estimation Resource; LGG, low-grade glioma; TCGA, The Cancer Genome Atlas.