Table 3.
Comparison of glomerular counts. For the non-sclerotic model, the model-annotation count is not significantly different from the reference segmentations, whereas the standard of care count is different from the reference segmentations. The same is true for the sclerotic model, which is not significantly different from the reference segmentations, whereas the standard of care has a significantly different count from the reference segmentations.
Manual segmentation | DL model | Pathology report | Manual segmentation versus DL model | Manual segmentation versus pathology report | DL model versus pathology report | |
---|---|---|---|---|---|---|
Average number (range) | Average number (range) | Average number (range) | ||||
Nonsclerotic | 84.6 ± 14.5 (14 to 253) | 85.0 ± 15.2 (18 to 265) | 75.6 ± 18.3 (11 to 306) | p = 0.837 | p = 1.3426e-6 | p = 1.085e-7 |
Sclerotic | 5.3 ± 1.7 (0 to 26) | 6.0 ± 1.9 (0 to 29) | 3.4 ± 1.2 (0 to 18) | p = 0.095 | p = 0.002 | p = 0.002 |
% Sclerosis | 5.5 ± 1.2 (0 to 18.75) | 6.4 ± 1.5 (0 to 21.48) | 4.6 ± 1.1 (0 to 18.56) | p = 0.385 | p = 0.256 | p = 0.060 |