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. 2021 Dec 6;15:799916. doi: 10.3389/fnins.2021.799916

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Copyright © 2021 Chen, Hu, Wu, Chen, Zhou, Chen, Xu and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Brain regions with significant static VMHC difference between TAO group and HCs. Compared with HCs, TAO group showed significantly decreased VMHC values in LG/CAL, MOG, PoCG, SPL, IPL, and PCu (P < 0.05, cluster-level FWE corrected). The cold color denotes relatively lower values in TAO group, and the color bar indicates the t-value from two-sample t-test between TAO group and HCs. VMHC, voxel-mirrored homotopic connectivity; TAO, thyroid-associated ophthalmopathy; HCs, healthy controls; LG, lingual gyrus; CAL, calcarine; MOG, middle occipital gyrus; PoCG, postcentral gyrus; SPL, superior parietal lobule; IPL, inferior parietal lobule; PCu, precuneus; FWE, family-wise error; L, left; R, right; sVMHC, static VMHC.