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. 2021 Dec 6;15:799916. doi: 10.3389/fnins.2021.799916

TABLE 1.

Demographic and clinical characteristics of TAO group and HCs.

Items TAO group (n = 28) HCs (n = 22) P-value
Age (years) 44.25 ± 12.71 44.27 ± 12.75 0.907a
Gender (female/male) 15/13 12/10 0.945b
Disease duration (months) 18.39 ± 20.90
CAS 2.54 ± 1.26
Visual acuity 0.81 ± 0.25 0.98 ± 0.18 0.009c
QoL scores
Visual functioning 61.95 ± 26.77
Appearance 66.65 ± 19.70
Total score of HARS 15.39 ± 8.51 2.68 ± 2.61 <0.001a
Total score of HDRS 15.25 ± 9.96 2.23 ± 1.93 <0.001a
Total score of MoCA 26.75 ± 2.66 29.09 ± 1.02 <0.001a

Data were presented as mean ± standard deviation unless otherwise indicated.

CAS, clinical activity score; QoL, quality of life; HARS, Hamilton Anxiety Rating Scale; HDRS, Hamilton Depression Rating Scale; MoCA, Montreal Cognitive Assessment; TAO, thyroid-associated ophthalmopathy; HCs, healthy controls; n, number of subjects.

aP-value with Mann–Whitney test.

bP-value with Chi-square test.

cP-value with two-sample t-test.