Table 4.
Basic characteristics of SAPS II scoring system.
| Characteristics | Overall (n = 6,122) | SPAS II <43 (n = 3,860) | SPAS II ≥ 43 (n = 2,262) | p |
|---|---|---|---|---|
| SPASII, median (IQR) | 38 (30, 48) | 32.0 (27.0, 37.0) | 52.0 (47.0, 60.0) | <0.001 |
| Age, median (IQR) | 66 (55, 76) | 63.0 (53.0, 73.0) | 71.0 (61.0, 79.0) | <0.001 |
| Male gender, n (%) | 3,704 (60.503) | 2,398 (62.124) | 1,306 (57.737) | <0.001 |
| BMI, median (IQR) | 27.84 (24.39, 31.84) | 27.9 (24.42, 31.98) | 27.77 (24.29, 31.63) | 0.303 |
| Comorbidities | ||||
| Drug abuse, n (%) | 208 (3.398) | 152 (3.938) | 56 (2.476) | 0.002 |
| Alcohol abuse, n (%) | 474 (7.743) | 301 (7.798) | 173 (7.648) | 0.832 |
| Coagulopathy, n (%) | 1,153 (18.834) | 545 (14.119) | 608 (26.879) | <0.001 |
| Liver disease, n (%) | 463 (7.563) | 244 (6.321) | 219 (9.682) | <0.001 |
| Renal failure, n (%) | 869 (14.195) | 357 (9.249) | 512 (22.635) | <0.001 |
| Hypothyroidism, n (%) | 617 (10.078) | 372 (9.637) | 245 (10.831) | 0.134 |
| Diabetes, n (%) | 1,448 (23.652) | 883 (22.876) | 565 (24.978) | 0.062 |
| Chronic pulmonary, n (%) | 1,179 (19.258) | 714 (18.497) | 465 (20.557) | 0.049 |
| Hypertension, n (%) | 758 (12.382) | 326 (8.446) | 432 (19.098) | <0.001 |
| Congestive heart failure, n (%) | 816 (13.329) | 353 (9.145) | 463 (20.469) | <0.001 |
| Laboratory test | ||||
| WBC mean, median (IQR) | 11.93 (8.9, 15.55) | 11.7 (9.0, 14.77) | 12.43 (8.72, 17.1) | <0.001 |
| Bun mean, median (IQR) | 18.33 (13.0, 29.4) | 15.67 (12.0, 21.5) | 27.5 (17.0, 44.33) | <0.001 |
| Sodium mean, median (IQR) | 138.0 (136.0, 140.2) | 138.0 (136.2, 140.0) | 138.0 (135.67, 140.71) | 0.720 |
| INR mean, median (IQR) | 1.3 (1.2, 1.5) | 1.3 (1.2, 1.4) | 1.4 (1.2, 1.7) | <0.001 |
| PT mean, median (IQR) | 14.65 (13.6, 16.2) | 14.42 (13.4, 15.65) | 15.25 (13.85, 17.6) | <0.001 |
| Potassium mean, median (IQR) | 4.19 (3.87, 4.5) | 4.15 (3.85, 4.44) | 4.24 (3.9, 4.65) | <0.001 |
| Platelet mean, median (IQR) | 175.33 (130.33, 233.33) | 179.33 (137.0, 233.0) | 168.5 (117.67, 234.0) | <0.001 |
| Lactate mean, median (IQR) | 1.93 (1.4, 2.7) | 1.88 (1.4, 2.5) | 2.12 (1.5, 3.15) | <0.001 |
| Hemoglobin mean, median (IQR) | 10.15 (9.15, 11.4) | 10.3 (9.25, 11.5) | 9.92 (9.0, 11.1) | <0.001 |
| Glucose mean, median (IQR) | 130.57 (116.0, 150.89) | 128.5 (115.33, 145.22) | 134.75 (117.6, 160.33) | <0.001 |
| Creatinine mean, median (IQR) | 0.95 (0.72, 1.37) | 0.87 (0.7, 1.1) | 1.23 (0.85, 2.25) | <0.001 |
| PH mean, median (IQR) | 7.38 (7.34, 7.41) | 7.38 (7.35, 7.42) | 7.36 (7.31, 7.4) | <0.001 |
| Vital sign | ||||
| SpO2 mean, median (IQR) | 97.77 (96.52, 98.81) | 97.82 (96.67, 98.82) | 97.64 (96.28, 98.81) | <0.001 |
| BT mean, median (IQR) | 36.81 (36.43, 37.24) | 36.84 (36.48, 37.24) | 36.77 (36.35, 37.24) | <0.001 |
| Res prate mean, median (IQR) | 18.12 (16.08, 21.17) | 17.72 (15.85, 20.41) | 19.0 (16.57, 22.61) | <0.001 |
| Mean bp mean, median (IQR) | 75.11 (70.17, 81.36) | 76.22 (71.22, 82.61) | 73.4 (68.32, 78.79) | <0.001 |
| Dias bp mean, median (IQR) | 58.39 (53.15, 64.3) | 59.56 (54.39, 65.59) | 56.63 (51.14, 62.15) | <0.001 |
| Sys bp mean, median (IQR) | 112.86 (105.52, 122.26) | 114.55 (107.05, 124.08) | 110.26 (103.03, 119.36) | <0.001 |
| Heart rate mean, median (IQR) | 85.83 (77.53, 96.52) | 84.89 (77.27, 94.66) | 87.35 (78.06, 99.97) | <0.001 |
| Primary outcome | ||||
| Death in-hospital, n (%) | 925 (15.109) | 293 (7.591) | 632 (27.940) | <0.001 |
| Death 28-day, n (%) | 1,114 (18.197) | 363 (9.404) | 751 (33.201) | <0.001 |
| Death 90-day, n (%) | 1,301 (21.251) | 446 (11.554) | 855 (37.798) | <0.001 |
| Death 1-year, n (%) | 1,606 (26.233) | 593 (15.363) | 1,013 (44.783) | <0.001 |
| Second outcome | ||||
| AKI 7-day, n (%) | 4,563 (74.534) | 2,621 (67.902) | 1,942 (85.853) | <0.001 |
| Hospital stay ≥ 14 days, n (%) | 2,092 (34.172) | 950 (24.611) | 1,142 (50.486) | <0.001 |
| ICU stay ≥ 3 days, n (%) | 3,422 (55.897) | 1,774 (45.959) | 1,648 (72.856) | <0.001 |
| Survival time, median (IQR) | 11.15 (6.26, 27.17) | 9.82 (5.86, 21.68) | 15.3 (7.94, 41.25) | <0.001 |
BMI, body mass index; WBC, white blood cell count; BUN, Blood urea nitrogen; PT, prothrombin time; INR, international normalized ratio; SOFA, sequential organ failure assessment; SPASII, simplified acute physiology score; AKI, acute kidney injury; ICU, the intensive care unit; SPO2, pulse oxygen saturation; PH,potential of hydrogen; BT,body temperature; Data are represented as median (interquartile range) or n (%).