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. 2021 Dec 6;9:755751. doi: 10.3389/fcell.2021.755751

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Copyright © 2021 Singh and Parte.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mature sperm-retained TH2B-associated loci overlap with activating modifications H3K4me3/H3K4me2 in sperm and two-cell embryos but not with the repressive marks in sperm. Heatmap and profile plot for various sperm-associated modified histones and their overlap with reference to TH2B MACS2 peak. Scale on the right-hand side reveals the intensity of overlap scores between the query set (TH2B BED) and sperm PTMs.