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. 2020 Sep 2:0748730420953335. doi: 10.1177/0748730420953335

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© 2020 The Author(s)

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Figure 1. — The top 10 infection phenotypes associated with relative circadian amplitude among participants of the UK Biobank, by −log10 of the Benjamini-Hochberg q-values. Cases were extracted by lifetime occurrence of ICD-10 codes and associations computed by a linear model controlling for age, sex, socioeconomic status, body mass index, smoking status, and self-reported overall health. Relative amplitude was computed as a ratio (M10-L5/M10+L5) where M10 and L5 are are the participant’s average activity levels of the ten hours of highest activity and five hours of the lowest activity, respectively ( Witting et al., 1990).