Table 1.
Clinical characteristics of ALS patients.
| All patients | ALS-ncie | ALS-cie | P-value | |
|---|---|---|---|---|
| n =124 | n = 76 | n = 48 | ||
| Male (%) | 58 | 63 | 50 | 0.15a |
| Education (year) | 9 (0–16) | 11 (4–16) | 7.5 (0–12) | <0.001c |
| Age at onset (year) | 53.6 ± 10.8 | 51.1 ± 10.4 | 57.5 ± 10.4 | 0.001b |
| Age at testing (year) | 54.6 ± 10.9 | 52.1 ± 10.5 | 58.6 ± 10.3 | 0.001b |
| Duration of illness (month) | 11 (1–64) | 10.5 (2–49) | 11 (1–64) | 0.41c |
| BMI (kg/m2) | 21.6 (15.2–28.3) | 21.6 (15.2–28.3) | 21.6 (17.3–26.9) | 0.93c |
| Site of onset: bulbar/limb/respiratory/mixed (%) | 18/75/1/6 | 16/78/1/5 | 21/71/0/8 | 0.57a |
| ALSFRS-R score | 41 (15–48) | 41.5 (19–48) | 40 (15–47) | 0.57c |
| Uric acid (μmol/L) | 310.4 ± 76.0 | 323.8 ± 77.1 | 289.3 ± 70.0 | 0.01b |
ALS-cie, amyotrophic lateral sclerosis with cognitive impairment; ALS-ncie, amyotrophic lateral sclerosis without cognitive impairment; BMI, body mass index; ALSFRS-R, amyotrophic lateral sclerosis functional rating scale-revised.
a
χ2-test.
b
Independent t-test with values presented as mean ± SD.
c
Mann-Whitney-U-test with values presented as median (range).