Table 2.
Predictive ability of MRI abnormalities and general movements assessment for adverse outcome*
| Sensitivity | Specificity | PPV | NPV | Accuracy | |
| Moderately/Severely abnormal MRI† | 61.5 (31.6 to 86.1) | 90.0 (73.5 to 97.9) | 72.7 (45.6 to 89.5) | 84.4 (72.9 to 91.6) | 81.4 (66.6 to 91.6) |
| Moderate/Severe BGT injury | 61.5 (31.6 to 86.1) | 96.7 (82.8 to 99.9) | 88.9 (52.6 to 98.3) | 85.3 (74.4 to 92.1) | 86.1 (72.1 to 94.7) |
| Absent PLIC | 46.2 (19.2 to 74.9) | 100.0 (88.4 to 100.0) | 100.0 | 81.1 (72.2 to 87.6) | 83.7 (69.3 to 93.2) |
| Equivocal/Absent PLIC | 76.9 (46.2 to 95.0) | 93.3 (77.9 to 99.2) | 83.3 (55.9 to 95.2) | 90.3 (77.5 to 96.2) | 88.4 (74.9 to 96.1) |
| Absent FMs | 60.0 (26.2 to 87.8) | 89.3 (71.8 to 97.7) | 66.7 (38.0 to 86.7) | 86.2 (74.3 to 93.1) | 81.6 (65.7 to 92.3) |
| Sporadic or absent FMs | 70.0 (34.8 to 93.3) | 57.1 (37.2 to 75.5) | 36.8 (24.4 to 51.3) | 84.2 (66.3 to 93.6) | 60.5 (43.4 to 76.0) |
Data are % (95% CI).
*Adverse outcome defined as death, cerebral palsy with Gross Motor Function Classification System level 3–5 or Bayley-III cognitive and/or motor composite score <85.
†Moderately/Severely abnormal MRI defined as moderate/severe BGT score and/or absent PLIC and/or severe WM score.
BGT, basal ganglia and thalami; FMs, fidgety movements; NPV, negative predictive value; PLIC, posterior limb of the internal capsule; PPV, positive predictive value.