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. 2021 Nov 20;41(11):1592–1599. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2021.11.01

1.

患者的临床特征

Clinical characteristics of the patients

Variables Quartile 1 (n=289) Quartile 2 (n=287) Quartile 3 (n=292) Quartile 4 (n=289) Statistics P
BMI: Body mass index; NC: neck circumference; WC: Waist circumference; WHR: Waist/hip ratio; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; AHI: The apnea-hypopnea index; ODI: The oxygen desaturation index; MSpO2: The mean pulse oxygen saturation; LSpO2: The lowest pulse oxygen saturation; T90: Percentage of the times for SaO2 < 90% in total monitoring time during overnight sleep; TST: Total sleep time; TSA90: The duration of time with SaO2 < 90%; OSA: Obstructive sleep apnea; LAT: The longest apnea time; MAT: The mean apnea time; FPG: Fasting plasma glucose; TG: Triglyceride; CHD: Coronary heart disease; COPD: Chronic obstructive pulmonary disease.
Demographics
  Age[year, M(Q1, Q3)] 67.0(63.0, 72.0) 65.0(62.0, 72.0) 66.0(62.0, 71.0) 65.0(61.0, 70.0) 18.551 < 0.001
  Male[n(%)] 158(54.67) 161(56.10) 195(66.78) 190(65.74) 14.569 0.02
  BMI[kg/m2, M(Q1, Q3)] 25.25(22.66, 27.47) 25.51(23.44, 27.69) 26.30(24.34, 29.01) 28.34(25.95, 31.14) 121.235 < 0.001
  WC[cm, M(Q1, Q3)] 88.0(80.0, 95.0) 89.0(78.0, 98.0) 90.0(80.0, 10.0) 98.0(87.0, 107.0) 68.371 < 0.001
  NC[cm, M(Q1, Q3)] 37.50(35.0, 40.0) 38.0(35.50, 40.0) 38.0(36.0, 40.0) 38.0(35.0, 40.0) 1.407 0.704
  WHR[%, M(Q1, Q3)] 0.80(0.70, 0.85) 0.70(0.70, 0.80) 0.80(0.70, 0.90) 0.90(0.80, 1.10) 28.791 < 0.001
  SBP[mmHg, M(Q1, Q3)] 128.0(120.0, 135.0) 129.0(120.0, 138.0) 130.0(120.0, 140.0) 130.0(123.0, 139.0) 9.858 0.020
  DBP[mmHg, M(Q1, Q3)] 76.0(70.0, 80.0) 75.0(70.0, 81.0) 76.0(70.0, 83.25) 75.0(70.0, 80.0) 4.082 0.253
  Smoking[n(%)] 57(19.79) 57(19.86) 75(25.68) 67(23.18) 4.097 0.251
  Drinking[n(%)] 26(9.03) 29(10.10) 36(12.33) 25(8.65) 2.641 0.45
  TG[mmol/L, M(Q1, Q3)] 1.20(0.91, 1.76) 1.31(0.99, 1.76) 1.23(0.89, 1.71) 1.42(1.01, 1.94) 13.912 0.003
  FPG[mmol/L, M(Q1, Q3)] 5.55(4.96, 6.21) 5.63(5.04, 6.34) 5.72(5.03, 6.57) 5.70(5.12, 6.43) 8.313 0.040
  HDL[mmol/L, M(Q1, Q3)] 1.13(0.95, 1.43) 1.18(0.96, 1.44) 1.08(0.88, 1.37) 1.10(0.90, 1.35) 10.124 0.018
Sleep parameters
  AHI[events/h, M(Q1, Q3)] 9.30(6.70, 11.90) 20.80(17.90, 23.75) 34.40(30.65, 39.73) 59.10(51.80, 69.90) 1083.750 < 0.001
  TST[h, M(Q1, Q3)] 7.05(6.23, 7.31) 7.10(6.32, 7.59) 6.96(5.89, 7.36) 7.18(6.30, 7.75) 16.183 0.01
  ODI[events/h, M(Q1, Q3)] 8.20(4.60, 12.0) 15.60(11.15, 21.85) 28.50(22.0, 36.50) 52.0(42.60, 62.90) 717.264 < 0.01
  TSA90[min, M(Q1, Q3)] 3.41(0.70, 34.02) 8.30(1.90, 29.90) 17.02(4.27, 51.78) 68.0(19.0, 150.50) 185.857 < 0.001
  MSpO2[%, M(Q1, Q3)] 94.0(92.0, 95.0) 94.0(92.0, 95.0) 94.0(92.0, 95.0) 92.0(90.0, 94.0) 86.579 < 0.001
  LSpO2[%, M(Q1, Q3)] 84.0(80.0, 87.0) 82.0(77.0, 86.0) 79.0(72.0, 84.0) 72.0(63.0, 79.0) 227.547 < 0.001
  MAT[s, M(Q1, Q3)] 21.35(17.40, 24.33) 21.20(18.0, 24.84) 22.91(20.21, 26.0) 23.81(20.98, 29.0) 72.369 < 0.001
  LAT[s, M(Q1, Q3)] 30.40(14.0, 44.0) 40.50(28.0, 56.0) 56.0(41.50, 76.30) 67.0(47.0, 88.0) 288.518 < 0.001
  T90[%, M(Q1, Q3)] 0.01(0.0, 0.08) 0.02(0.0, 0.07) 0.05(0.01, 0.13) 0.17(0.05, 0.39) 182.448 < 0.001
Medical history
  COPD[n(%)] 24(8.30) 17(5.92) 22(7.53) 17(5.88) 1.958 0.581
  CHD[n(%)] 51(17.65) 71(24.74) 77(26.37) 66(22.84) 7.057 0.070
  Carotid atherosclerosis[n(%)] 93(32.18) 63(21.95) 78(26.71) 62(21.45) 11.379 0.010
  Hyperlipidemia[n(%)] 92(31.83) 76(26.48) 78(26.71) 79(27.34) 2.729 0.435
  Hypertension[n(%)] 179(61.94) 173(60.28) 180(61.64) 210(72.66) 12.390 0.06
  Diabetes[n(%)] 57(19.72) 63(21.95) 83(28.42) 83(28.72) 9.698 0.021
  Atrial fibrillation[n(%)] 18(6.23) 17(5.92) 40(13.70) 22(7.61) 17.933 0.06
  MetS[n(%)] 175(60.55) 164(57.54) 183(62.67) 181(62.63) 2.451 0.484