Table 1.
Estimated number of new persons diagnosed with SLE in the USA in 2018
| Female | |||
| Race/ethnicity (number of sites in the analysis) | SLE incidence* per 100 000 (95% CI) | Population denominator | Estimated SLE cases in the USA, n (95% CI) |
| Race | |||
| Black (4) | 15.9 (12.5 to 20.3) | 24 880 722 | 3956 (3110 to 5051) |
| White (4) | 5.7 (4.9 to 6.7) | 130 137 989 | 7418 (6377 to 8719) |
| Asian/PI (2) | 7.6 (5.5 to 10.4) | 12 544 896 | 953 (690 to 1305) |
| AI/AN (1) | 10.4 (6.6 to 14.6) | 2 238 966 | 233 (148 to 327) |
| Total† | 8.7 (8.1 to9.4) | 169 802 573 | 12 560 (10 325 to 15 402) |
| Ethnicity | |||
| Hispanic‡ (2) | 6.8 (6.2 to 7.6) | 30 689 083 | 2087 (1903 to 2332) |
| Male | |||
| Incidence* per 100 000 (95% CI) |
Population denominator | Estimated SLE cases in the USA, n (95% CI) | |
| Race | |||
| Black (4) | 2.4 (1.8 to 3.0) | 22 961 129 | 551 (413 to 689) |
| White (4) | 0.8 (0.6 to 1.1) | 127 942 583 | 1024 (768 to 1407) |
| Asian/PI (2) | 0.4 (0.2 to 0.6) | 11 660 533 | 47 (23 to 70) |
| AI/AN (1) | 3.8 (1.6 to 7.8) | 2 134 870 | 81 (34 to 167) |
| Total† | 1.2 (0.9 to 1.6) | 164 699 115 | 1703 (1238 to 2333) |
| Ethnicity | |||
| Hispanic‡ (2) | 0.9 (0.4 to 1.9) | 31 281 605 | 282 (125 to 594) |
SLE cases were defined according to the 1997 revised American College of Rheumatology criteria.
*Estimates for black and white persons are based on pooled estimates from the four state-based registries; Asian/PI and Hispanics are based on pooled estimates from California and New York; AI/AN estimates are based on the Indian Health Service registry.
†The pooled ‘total’ incidence estimate includes black, white and Asian/PI. Since the AI/AN incidence was based on one registry and was significantly higher, it was not included in the pooled incidence per 100 000.
‡Hispanic ethnicity is not mutually exclusive from the race categories, that is, all Hispanic persons are included in one of the race categories. Thus, the pooled estimates do not incorporate the Hispanic rates since that would lead to duplicate counting. Estimates for Hispanics are based on pooled estimates from California and New York.
AI/AN, American Indian/Alaska Native; Asian/PI, Asian/Pacific Islander.