Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 6;12:788558. doi: 10.3389/fphar.2021.788558

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Li, Wang, Chen, Zhou, Zhang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of UDCA treatment on hepatic bile acid–related genes expression in NASH mice. (A) UDCA treatment did not activate the suppressed FXR signal pathway in NASH mice. (B) Proposed mechanism of UDCA treatment alleviating hepatic inflammation in NASH mice. Values represent mean ± standard deviation with *p < 0.05, **p < 0.01, and not significant (ns) vs HFHC_12w group. Abbreviation: UDCA, ursodeoxycholic acid; NASH, non-alcoholic steatohepatitis; FXR, farnesoid X receptor; HFHC, high-fat high-cholesterol.