Table 5.
Penetrance tables of the twenty-two epistasis models with a different set of parameters
| Model id | h2 | MAF | Penetrance function | |||
|---|---|---|---|---|---|---|
| Genotypes (SNP A) | Genotypes (SNP B) | |||||
| BB | Bb | bb | ||||
| model 1 | 0.005 | 0.05 | AA | 0.0980 | 0.0980 | 0.0980 |
| Aa | 0.0980 | 0.2989 | 0.5222 | |||
| aa | 0.0980 | 0.5222 | 0.9121 | |||
| model 2 | 0.005 | 0.1 | AA | 0.0960 | 0.0960 | 0.0960 |
| Aa | 0.0960 | 0.1971 | 0.2824 | |||
| aa | 0.0960 | 0.2824 | 0.4047 | |||
| model 3 | 0.005 | 0.2 | AA | 0.0921 | 0.0921 | 0.0921 |
| Aa | 0.0921 | 0.1445 | 0.1810 | |||
| aa | 0.0921 | 0.1810 | 0.2266 | |||
| model 4 | 0.005 | 0.5 | AA | 0.0782 | 0.0782 | 0.0782 |
| Aa | 0.0782 | 0.1054 | 0.1223 | |||
| aa | 0.0782 | 0.1223 | 0.1420 | |||
| model 5 | 0.02 | 0.05 | AA | 0.0958 | 0.0958 | 0.0958 |
| Aa | 0.0958 | 0.5331 | 0.5331 | |||
| aa | 0.0958 | 0.5331 | 0.5331 | |||
| model 6 | 0.02 | 0.1 | AA | 0.0918 | 0.0918 | 0.0918 |
| Aa | 0.0918 | 0.3192 | 0.3192 | |||
| aa | 0.0918 | 0.3192 | 0.3192 | |||
| model 7 | 0.02 | 0.2 | AA | 0.0836 | 0.0836 | 0.0836 |
| Aa | 0.0836 | 0.2099 | 0.2099 | |||
| aa | 0.0836 | 0.2099 | 0.2099 | |||
| model 8 | 0.02 | 0.5 | AA | 0.0519 | 0.0519 | 0.0519 |
| Aa | 0.0519 | 0.1374 | 0.1374 | |||
| aa | 0.0519 | 0.1374 | 0.1374 | |||
| model 9 | 0.02 | 0.05 | AA | 0.0804 | 0.1918 | 0.1918 |
| Aa | 0.1918 | 0.0804 | 0.0804 | |||
| aa | 0.1918 | 0.0804 | 0.0804 | |||
| model 10 | 0.02 | 0.1 | AA | 0.0717 | 0.1636 | 0.1636 |
| Aa | 0.1636 | 0.0717 | 0.0717 | |||
| aa | 0.1636 | 0.0717 | 0.0717 | |||
| model 11 | 0.02 | 0.2 | AA | 0.0608 | 0.1459 | 0.1459 |
| Aa | 0.1459 | 0.0608 | 0.0608 | |||
| aa | 0.1459 | 0.0608 | 0.0608 | |||
| model 12 | 0.02 | 0.5 | AA | 0.0671 | 0.1548 | 0.1548 |
| Aa | 0.1548 | 0.0671 | 0.0671 | |||
| aa | 0.1548 | 0.0671 | 0.0671 | |||
| model 13 | 0.01 | 0.2 | AA | 0.6377 | 0.4884 | 0.3826 |
| Aa | 0.4638 | 0.7645 | 0.9566 | |||
| aa | 0.5798 | 0.5624 | 0.7189 | |||
| model 14 | 0.01 | 0.2 | AA | 0.2216 | 0.2758 | 0.1414 |
| Aa | 0.2587 | 0.1690 | 0.4013 | |||
| aa | 0.2781 | 0.1279 | 0.4196 | |||
| model 15 | 0.01 | 0.2 | AA | 0.2216 | 0.2758 | 0.1414 |
| Aa | 0.2587 | 0.1690 | 0.4013 | |||
| aa | 0.2781 | 0.1279 | 0.4196 | |||
| model 16 | 0.01 | 0.2 | AA | 0.1391 | 0.1882 | 0.2214 |
| Aa | 0.1901 | 0.1114 | 0.0198 | |||
| aa | 0.2056 | 0.0514 | 0.2530 | |||
| model 17 | 0.01 | 0.2 | AA | 0.1391 | 0.1882 | 0.2214 |
| Aa | 0.1901 | 0.1114 | 0.0198 | |||
| aa | 0.2056 | 0.0514 | 0.2530 | |||
| model 18 | 0.01 | 0.4 | AA | 0.1032 | 0.0634 | 0.1242 |
| Aa | 0.0978 | 0.0858 | 0.0693 | |||
| aa | 0.0210 | 0.1467 | 0.0595 | |||
| model 19 | 0.01 | 0.4 | AA | 0.1852 | 0.2908 | 0.2340 |
| Aa | 0.2860 | 0.2009 | 0.2770 | |||
| aa | 0.2486 | 0.2661 | 0.1657 | |||
| model 20 | 0.01 | 0.4 | AA | 0.0731 | 0.0418 | 0.0146 |
| Aa | 0.0240 | 0.0639 | 0.0591 | |||
| aa | 0.0682 | 0.0188 | 0.0946 | |||
| model 21 | 0.01 | 0.4 | AA | 0.0462 | 0.1275 | 0.0694 |
| Aa | 0.1150 | 0.0667 | 0.0971 | |||
| aa | 0.1067 | 0.0691 | 0.1085 | |||
| model 22 | 0.01 | 0.4 | AA | 0.0950 | 0.1222 | 0.1267 |
| Aa | 0.0973 | 0.1294 | 0.0999 | |||
| aa | 0.2014 | 0.0439 | 0.1222 | |||