Table 2.
Top 20 upregulated and downregulated genes
| Symbol | Ratio NP/P | Abs. FC | P Value |
|---|---|---|---|
| Most overrepresented in Nonprogr | |||
| SLC12A1 | 14.31 | 14.31 | 1.24E−02 |
| AC146944.1 | 11.82 | 11.82 | 6.37E−03 |
| IGHA2 | 9.18 | 9.18 | 1.40E−02 |
| IGLL5 | 9.13 | 9.13 | 8.78E−03 |
| SLC9A4 | 8.84 | 8.84 | 1.51E−03 |
| HPD | 8.05 | 8.05 | 1.68E−02 |
| IGKV1-5 | 7.98 | 7.98 | 1.44E−03 |
| GRIA4 | 6.53 | 6.53 | 1.27E−02 |
| H3F3AP4 | 6.46 | 6.46 | 9.16E−03 |
| IGHV4-61 | 6.14 | 6.14 | 2.43E−02 |
| SNORD115-11 | 5.89 | 5.89 | 2.41E−02 |
| IGLV2-23 | 5.78 | 5.78 | 1.12E−02 |
| IGLV2-14 | 5.77 | 5.77 | 3.10E−03 |
| CLEC18C | 5.62 | 5.62 | 2.11E−02 |
| SNORA38 | 5.62 | 5.62 | 3.51E−04 |
| MST1P2 | 5.60 | 5.60 | 4.75E−03 |
| IGKV1-39 | 5.55 | 5.55 | 1.03E−02 |
| MST1L | 5.54 | 5.54 | 2.48E−02 |
| LTF | 5.50 | 5.50 | 3.37E−03 |
| SYT7 | 5.5 | 5.50 | 0.00595 |
| Most overrepresented in Progr | |||
| SV2B | 0.06737229 | 14.8429 | 0.000319 |
| FAM86B2 | 0.077412071 | 12.91788 | 0.000404 |
| NPIPB9 | 0.082203939 | 12.16487 | 2.76E-05 |
| ANKRD20A7P | 0.085199087 | 11.73721 | 0.000611 |
| LBP | 0.092082598 | 10.85982 | 0.000551 |
| SNORD116-18 | 0.097088878 | 10.29984 | 0.01859 |
| ADGRB1 | 0.10462215 | 9.558205 | 0.000124 |
| ASAH2 | 0.106344157 | 9.403432 | 0.003289 |
| PLK4 | 0.108067443 | 9.253481 | 0.002456 |
| STAG3 | 0.108558859 | 9.211593 | 0.000654 |
| ZNF321P | 0.109969942 | 9.093394 | 0.000128 |
| AC135048.4 | 0.113068345 | 8.844208 | 6.67E-05 |
| NPIPB1P | 0.113446458 | 8.814731 | 0.001067 |
| SYS1-DBNDD2 | 0.118191167 | 8.460869 | 0.00063 |
| RMRP | 0.122271935 | 8.178492 | 0.023045 |
| RASA4CP | 0.123307134 | 8.109831 | 0.008782 |
| AC239799.1 | 0.123616908 | 8.089508 | 0.011112 |
| DCUN1D2 | 0.125942208 | 7.94015 | 3.24E-05 |
| FAM131C | 0.128131248 | 7.804497 | 0.000418 |
| CAMK2B | 0.132235909 | 7.562242 | 0.000196 |
Top 20 upregulated and downregulated genes in nonprogressor and progressor patients. The 20 genes with the lowest and highest FC are displayed. AGAP-AS1 was not found among these genes
Nonprogr nonprogressors; Progr progressors