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. 2021 Dec 20;27:159. doi: 10.1186/s10020-021-00421-0

Table 8.

Main characteristics of the studies included in the review of other system tumors

Study Tumor types Sample size
(Normal: Tumor)
Detection Method P value TNM
(p value)
LNM
(p value)
DM
(p value)
OS
(p value)
References
Li Osteosarcoma (145: 145) qRT-PCR p < 0.01 p = 0.007 / p = 0.008 p < 0.001 Li et al. 2017)
Xu Osteosarcoma (66: 66) qRT-PCR p < 0.01 / / / / Xu et al. 2017)
Wang Osteosarcoma (64: 64) qRT-PCR p < 0.01 / / p = 0.012 p = 0.034 Wang et al. 2019)
Li Osteosarcoma (35: 35) qRT-PCR p < 0.01 / / / / Li et al. 2019b)
Lv Osteosarcoma (34: 34) qRT-PCR p < 0.05 / / / / Lv et al. 2018)
Wen Osteosarcoma (30: 30) qRT-PCR p < 0.001 / / / / Wen et al. 2020)
Hai Osteosarcoma (15: 38) qRT-PCR p < 0.001 / / / p = 0.0221 Hai et al. 2021)
Zhou Bladder cancer (52: 52) qRT-PCR p < 0.01 p = 0.001 p = 0.001 p = 0.001 p = 0.039 Zhou et al. 2019)
Xiong Bladder cancer (67: 67) qRT-PCR p < 0.01 p = 0.01 / / / Xiong et al. 2017)
Hu Bladder cancer (52: 52) qRT-PCR p < 0.05 p = 0.012 p = 0.042 / p = 0.0332 Hu et al. 2017)
Xu Retinoblastoma (53: 87) qRT-PCR p < 0.05 / / / p < 0.05 Xu and Tian 2020)
Hu Retinoblastoma (6: 30) qRT-PCR p < 0.01 p < 0.01 / / / Hu et al. 2018)
Cheng Retinoblastoma (7: 53) qRT-PCR p < 0.05 / / / / Cheng et al. 2019)
Wang Retinoblastoma (8: 20) qRT-PCR p < 0.001 / / / / Wang et al. 2020d)
Zhao Retinoblastoma (54: 54) qRT-PCR p < 0.001 / / / / Zhao et al. 2020)
Yang Retinoblastoma (30: 30) qRT-PCR p < 0.05 / / / / Yang et al. 2020)
Yao Retinoblastoma (6: 25) qRT-PCR p < 0.05 / / / / Yao et al. 2020)
Zhu Cervical cancer (52: 52) qRT-PCR p < 0.01 p = 0.04 / p = 0.027 p = 0.015 Zhu et al. 2018a)
Chen Cervical cancer (30: 30) qRT-PCR p < 0.001 p = 0.033 p = 0.038 / / Chen et al. 2019b)
Liu Cervical cancer (35: 35) qRT-PCR p < 0.05 p < 0.05 / / p < 0.01 Liu et al. 2020)
Xu Thyroid cancer (36: 36) qRT-PCR p < 0.01 p < 0.01 p < 0.01 / / Xu et al. 2018b)
Liu Thyroid cancer (77: 77) qRT-PCR p < 0.01 / / / p = 0.025 Liu et al. 2018)
Du Thyroid cancer (24: 24) qRT-PCR p < 0.01 / / / / Du et al. 2021)
Song Nasopharyngeal cancer (108: 108) qRT-PCR p < 0.05 / / / p = 0.0005 Song et al. 2016)
Cheng Nasopharyngeal cancer (10: 20) qRT-PCR p < 0.05 / / / / Cheng et al. 2018)
Shi Nasopharyngeal cancer (40: 40) qRT-PCR p < 0.05 / / / / Shi et al. 2020)
Zhao Nasopharyngeal cancer (25: 25) qRT-PCR p < 0.05 / / / / Zhao et al. 2020)
Hao Melanoma (15: 15) qRT-PCR p < 0.01 / / / / Hao et al. 2021)
Wang Leukemia (20: 62) qRT-PCR p < 0.05 / / / / Wang et al. 2020a)