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Preclinical models for genetic epilepsy. A: General overview of the preclinical models used in epilepsy. B: iPSC-derived brain cells conjoined with gene editing and functional analyses provide clues on molecular pathways of the pathophysiology of epilepsy and can help to identify drug resistance, toxicity, and novel targets compounds. (A higher resolution / colour version of this figure is available in the electronic copy of the article).
