Study	Species	Sexes	Sexes Combined or Separated	Sample Size	Singular/ Chronic Dosing	Chronic Timing	Dose (mg/kg)	Route	Treatment Age (PD)	Testing Age (PD)	Temperature (°C)	Social Restriction	Males	Females	Both
Morley 2000 [228]	Rat	Males	NA	56	Singular	NA	1.25, 2.5, 5	i.p.	85-95	99-109	22	Nil	Decreased aggression time. 5 mg/kg: increased social interaction time, locomotion. 1.25 and 2.5 mg/kg had no effect on locomotion or social interaction duration	NA	NA
Morley 2001 [91]	Rat	Males	NA	32	Chronic	Each of 4 hours on 2 consecutive days	5	i.p.	75-95	160-180	22	Nil	Decreased total interaction time and frequency, rearing frequency, locomotion.	NA	NA
Morley 2001 [91]	Rat	Males	NA	32	Singular	NA	5	i.p.	75-95	160-180	22	Nil	Decreased total interaction time and frequency, rearing frequency, locomotion, social interaction.	NA	NA
Morley 2005 [81]	Rat	Males	NA	112	Singular	NA	5	i.p.	50-90	50-90	28	5 mins.	Increased total social interaction time (adjacent lying, approach), decreased anogenital sniffing and rearing. Serotonin syndrome: greater turning, low body posture, piloerection.	NA	NA
Morley-Fletcher 2002 [190]	Mouse	Males	NA	30	Chronic	Once on each of 3 days, 2 days apart	5, 10	i.p.	28, 38, 52	80	21	Nil	Altered environmental exploration time (dosed at early and late adolescence: dose-dependent increase; dosed at middle-adolescence: decrease). Decreased self-grooming. Decreased freezing time (dosed at early adolescence).	NA	NA
Navarro 1998 [89]	Mouse	Males	NA	96	Singular	NA	0.5, 1.25, 2.5, 5, 10, 15, 20	i.p.	42	42	20	30 days (for aggression)	Decreased aggression (threat, attack) and social exploration; increased distant exploration, avoidance and defence. 5-20 mg/kg: decreased threat/attack time. 2.5-20 mg/kg: increased distant exploration. 5-20 mg/kg: increased non-social exploration, avoidance/defence; decreased social exploration. 1.25-20 mg/kg: decreased digging. 2.5, 20 mg/kg: decreased grooming.	NA	NA
Navarro 2004 [96]	Mouse	Males	NA	40	Singular	NA	1, 8, 15	i.p.	25-30g	30 mins. later	20	Nil	1, 8, 15 mg/kg: decreased social-investigation time. 8, 15 mg/kg: decreased digging, increased avoidance/flee.	NA	NA
Navarro 2004 [90]	Mouse	Males	NA	120	Singular	Experimental day 7	1.25, 2.5, 5	i.p.	25-30g	30 mins. after last injection	21	30 days	Increased non-social exploration. 2.5, 5 mg/kg: decreased digging time, threat, attack; increased distant exploration. 5 mg/kg: increased avoidance/flee, defence/submission.	NA	NA
Navarro 2004 [90]	Mouse	Males	NA	120	Chronic	Experimental days 1-7, daily	1.25, 2.5, 5	i.p.	25-30g	31 mins. after last injection	21	30 days	1.25 mg/kg: increased digging. 2.5 mg/kg: increased exploration from distance, decreased non-social exploration behaviors.	NA	NA