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. 2021 Dec 20;20:225. doi: 10.1186/s12934-021-01713-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — The phaC₂ is the only PhaC polymerase gene in Cobetia sp. MC34. Gene synteny for the up-and downstream region of the PHA polymerase genes phaC₁ and phaC₂ found in selected Cobetia species. The phaCAB operon in C. necator is included for reference. The gene synteny of the phaC₂ region is shared between Cobetia sp. MC34, Halomonas sp. SF2003 and Cobetia marina DSM 4741^T. A putative non-homologues phaC₂ variant (striped symbol) is also found in H. bluephagenesis TD01 but with different genes located in the upstream region. Gene abbreviations: phaC_1/2 Poly(3-hydroxyalkanoate) polymerase subunit PhaC, PHA polymerase (EC 2.3.1.-), phaA Acetyl-CoA acetyltransferase (EC 2.3.1.9), phaB Acetoacetyl-CoA reductase (EC 1.1.1.36), phaP Phasin, atp ATP-metabolism genes, fabI (Enoyl-[acyl-carrier-protein] reductase [NADH], bi-pta bifunctional enoyl-CoA hydratase/phosphate acetyltransferase, afp Aminohydrolase family protein, hyp hypothetical protein of unknown function, lip lipoyl synthase and transferase, lysR LysR family transcriptional regulator