FIG. 1.
Amino acid sequence alignment of dMediator Homologs. (A) Mediator homologs conserved in Drosophila, human, and yeast (denoted by prefixes “d,” “h,” and “y,” respectively). The conserved residues are marked with boxes (black boxes for residues where all three sequences are identical or similar; gray boxes where two of the three are identical or similar). Only the conserved regions are shown. (B) Metazoan-specific Mediator homologs. The conserved amino acid sequences are marked as in panel A. hp28b and hp34 are the human homologs of mouse Mediator proteins p28b and p34 (13).