Table 1.

List of reported cases in literature of primitive ovarian PMP associated with teratoma

Number of reported cases	Age at diagnosis	Laterality / size of ovarian tumor	Histological type of mucinous ovarian tumor	Immunohistochemical profile of mucinous ovarian tumor	Percentage and composition of teratomatous elements	Appendix examination	Therapeutic strategy	Follow-up data	Bibliographical reference
3	35	right / 22 cm	borderline with focal cystadenocarcinoma	CK7-, CK20+	4%, squamous epithelium and adnexal glands	Ma and Mi: normal	cytoreductive surgery	death after disease progresion at 49 mo	[28] Ronnett et al. Am J Surg Pathol. 2003.
	81	left / 7 cm	cystadenoma	CK7-, CK20+	8%, squamous epithelium and sebaceous glands	Ma and Mi: normal	cytoreductive surgery	survival without relapse at 54 mo
	89	left / 15 cm	borderline	CK7-, CK20+	11%, squamous epithelium and cartilage	Ma and Mi: normal	cytoreductive surgery	survival without relapse at 48 mo
1	39	left / 14 cm	cystadenoma	CK7-, CK20+	low, squamous epithelium and adnexal glands	Ma and Mi: normal	cytoreductive surgery	survival without relapse at 6 mo	[29] Pranesh et al. J Clin Pathol. 2005.
1	67	left / 20 cm	borderline	CK7-, CK20+	low, dermoid cyst	NA (appendicectomy 42 years ago)	cytoreductive surgery	survival without relapse at 6 mo	[30] Marquette et al. Int J Gynecol Pathol. 2006.
2	38	left / 14 cm	borderline	CK7-, CK20+	5–10%, squamous epithelium and adnexal glands	Ma and Mi: normal	cytoreductive surgery	survival without relapse at 24 mo	[31] Stewart et al. Pathology. 2006.
	58	right / 16.5 cm	borderline	CK7-, CK20+	5–10%, squamous epithelium and adnexal glands	Ma and Mi: normal	cytoreductive surgery	survival without relapse at 21 mo
1	45	left / 12 cm	cystadenocarcinoma	NA	low, squamous epithelial and sebaceous glands	Ma and Mi: normal	cytoreductive surgery	NA	[32] Mandal et al. Arch Gynecol Obstet. 2008.
10	57	NA / NA	cystadenoma	CK7-, CK20+ (88%) CK7+, CK20- (13%)	low, squamous epithelium and adnexal glands, more or less other mature tissues	Ma and Mi: normal	cytoreductive surgery	NA	[33] McKenney et al. Am J Surg Pathol. 2008.
	36	NA / 25 cm	borderline			Ma and Mi: normal		NA
	54	NA / 14 cm	borderline			Ma and Mi: normal		survival without relapse at 24 mo
	41	NA / 25 cm	borderline			NA		NA
	42	NA / 7 cm	borderline			Ma and Mi: normal		survival without relapse at 27 mo
	47	NA / 20 cm	borderline			Ma and Mi: normal		survival without relapse at 23 mo
	28	NA / 22 cm	borderline			Ma and Mi: normal		survival without relapse at 61 mo
	48	NA / NA	cystadenocarcinoma			NA		metastases to omentum and pelvic serosa at 29 mo
	21	NA / NA	cystadenocarcinoma			NA		died of other disease at 6 mo
	56	NA / NA	cystadenocarcinoma			Ma and Mi: normal		metastases to omentum, small bowel serosa and mesentery at diagnosis
2	46	right / 15 cm	borderline	CK7+, CK20+	NA, squamous epithelium and bone	Ma and Mi: normal	cytoreductive surgery	NA	[34] Hwang et al. Int J Gynecol Pathol. 2009.
	28	left / 40 cm	cystadenoma focally borderline		NA, squamous epithelium and adnexa	Ma without Mi: normal	cytoreductive surgery and adjuvant chemotherapy	NA
1	43	right / NA	borderline	CK7+, CK20-	NA, squamous epithelium	Ma and Mi: chronic appendicitis	cytoreductive surgery	survival without relapse at 6 mo	[35] Mohtaram et al. Pan Afr Med J. 2013.
1	45	right / 29 cm	borderline	CK7+, CK20-	skin and adnexa	Ma and Mi: normal	cytoreductive surgery	NA	[36] Choi et al. Pathology. 2016.
3	75	left / NA	borderline	CK7+, CK20+	NA	Ma and Mi: appendicitis	cytoreductive surgery	survival without relapse at 25 mo	[37] Yan et al. Cancer Manag Res. 2020.
	45	right / NA	borderline with focal cystadenocarcinoma	CK7+, CK20+	NA	Ma and Mi: appendicitis	cytoreductive surgery and HIPEC	survival with disease at 30 mo
	53	bilateral / NA	cystadenocarcinoma	CK7-, CK20+	NA	Ma and Mi: appendicitis	cytoreductive surgery and HIPEC	survival with disease at 29 mo
1	25	left / 8.4 cm	ruptured appendiceal-like mucocele associated with LAMN in an ovarian teratoma	CK7+, CK20+	skin and pilosebaceous annexes, serous and mucinous glands, respiratory epithelium, adipose tissue and smooth muscle and colonic wall	Ma and Mi: normal	cytoreductive surgery	survival without relapse at 5 mo	Present case report
total: 26 cases	mean age at diagnosis: 47.8

Ma macroscopic, Mi microscopic, mo months, NA Not Available, HIPEC Hyperthermic IntraPEritoneal Chemotherapy

Cytoreductive surgery relying on hysterectomy, bilateral salpingo-oophorectomy, appendicectomy and omentectomy