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. 2021 Dec 20;18:254. doi: 10.1186/s12985-021-01727-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Exploration of the beta diversity in the normal control (NC) and RV-infected (RV) groups was assessed by Weighted Unifrac ANOSIM analysis. A principal coordinate analysis (PCoA) plot of the similarities between the different groups based on UniFrac distance. Principal components PCOA1 and PCOA2 explained 60.73% and 13.57% of the variance, respectively. Analysis of Adonis of the bacterial communities in the colorectal contents of the RV and NC groups was based on unifrac distance (R < 0.438 > 0 indicates that the differences between the groups are significant; p < 0.001 indicates that the differences are significant)