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. Author manuscript; available in PMC: 2021 Dec 20.
Published in final edited form as: Nat Med. 2021 Apr 29;27(5):871–881. doi: 10.1038/s41591-021-01309-6

Figure S7.

Figure S7

Stability of subtypes across train-test split and replication datasets. (Top) Cortical renders showing, for each subtype across each dataset, regions with significantly different tau-PET signal compared to other within-dataset subtypes after FDR correction. Hot regions show greater tau-PET whereas cooler regions show lower signal. Remarkable similarity can be observed across subtypes, except S4, where lateralization switches from left to right. (Bottom) A heatmap showing similarity (spatial correlation) between subtypes across all four datasets. The diagonal represents the identity, whereas outlined boxes represent comparisons of the same subtype across cohorts.