Fig. 1.

Allocated dose (mean, SD) of study drug per intake in the last 6 weeks (AAD/6W). Subgroup factors presented are ERI category by quartile (a), iron repletion category (b), DM status (c), eGFR (d), primary disease of CKD (e), concomitant ACEi/ARB use (f), GNRI quintile (g), and PNI quartile (h). CKD, chronic kidney disease; ERI, erythropoiesis-stimulating agent resistance index; SD, standard deviation; eGFR, estimated glomerular filtration rate; DM, diabetes mellitus; ACEi/ARB, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker; GNRI, geriatric nutritional risk index; PNI, prognostic nutritional index; AAD/6W, average allocated dose of roxadustat or darbepoetin alfa per administration in the last 6 weeks.