Table 1.

Performance of prospectively scored ultrasound features for predicting lymph node malignancy on the overall dataset of 490 lymph nodes (disease prevalence 0.48)

	Sens.	Spec.	PPV	NPV	Acc. (95% CI)	TN	TP	FN	FP
Overall dataset (n = 490, disease prevalence 0.48)
Size ≥10 mm	0.75	0.64	0.66	0.73	0.70 (0.65–0.74)	163	178	59	90
Size ≥8 mm	0.89	0.46	0.61	0.81	0.67 (0.62–0.7l)	116	210	27	137
Echogenicity	0.62	0.81	0.75	0.69	0.72 (0.67–0.76)	204	147	90	49
Shape	0.68	0.60	0.61	0.67	0.64 (0.59–0.68)	151	162	75	102
Margin	0.83	0.35	0.54	0.69	0.58 (0.54–0.63)	88	197	40	165
CHS	0.91	0.29	0.54	0.77	0.59 (0.54–0.63)	73	215	22	180
CNS	0.15	0.98	0.85	0.55	0.58 (0.53–0.62)	247	35	202	6
US Canada score >3	0.64	0.82	0.77	0.71	0.73 (0.69–0.77)	208	152	85	45
US Canada score >4	0.12	0.99	0.94	0.55	0.57 (0.62–0.52)	251	29	208	2
Mean strain <115	0.90	0.44	0.60	0.82	0.66 (0.62–0.70)	111	213	24	142

PPV, positive predictive value; NPV, negative predictive value; Acc., accuracy; CI, confidence interval; TN, true negative; TP, true positive; FN, false negative; FP, false positive; CHS, central hilar structure; CNS, central necrosis sign.