A squamous cell carcinoma with discordant PD-L1 expression (<1% vs. ≥50%) between paired EBUS cytology (a, b) and bronchial biopsy (c, d). Hematoxylin-eosin (a, c) and PD-L1 clone 22C3 (b, d). Scale bar, 20 μm. PD-L1, programmed death-ligand 1; EBUS, endobronchial ultrasound.