Table V.
Univariate and multivariate Cox regression analysis of overall survival in patients with oral squamous carcinoma.
| Parameter | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Gender | ||||
| Female/male | 0.50 (0.25-0.98) | 0.045 | ||
| Tumour grade | ||||
| G1/G2+G3 | 2.00 (1.05-3.81) | 0.036 | 2.30 (1.17-4.52) | 0.016 |
| T classification | ||||
| T1+T2/T3+T4 | 1.97 (1.42-2.74) | < 0.001 | 1.77 (1.25-2.51) | 0.001 |
| N classification | ||||
| N0/N1+N2+N3 | 2.38 (1.32-4.29) | 0.004 | 2.14 (1.12-4.08) | 0.021 |
| Clinical stage | ||||
| I+II/III+IV | 1.66 (1.17-2.37) | 0.005 | ||
| HSP90 expression | ||||
| Positive/negative | 2.47 (1.14-5.33) | 0.021 | 2.78 (1.21-6.40) | 0.016 |
| p53 expression | ||||
| Positive/negative | 1.00 (0.96-1.04) | 0.918 | ||
| E-cadherin expression | ||||
| Positive/negative | 0.74 (0.41-1.33) | 0.311 | ||
| HPV16/18 expression | ||||
| Positive/negative | 2.18 (1.07-4.44) | 0.032 | ||
HR: hazard ratio; CI: confidence interval. Bold values indicate statistical significance.