Table 4.

Multivariable logistic regression analysis of risk factors for anastomotic leak and their associated point values

Variable	Odds Ratio (95% CI)	Points Assigned
Age, years
18–39	1.6 (1.2–2.1)	5
40–49	1.3 (1.0–1.6)	3
50–59	1.2 (1.0–1.4)	2
60–69	1.2 (1.0–1.4)	1
70–79	Reference	0
80+	1.1 (0.9–1.4)	1
Sex
Female	Reference	0
Male	1.4 (1.2–1.5)	3
Tobacco use
No	Reference	0
Yes	1.5 (1.3–1.8)	4
Hematocrit < 30%
No	Reference	0
Yes	1.3 (1.0–1.7)	3
Missing	1.1 (0.9–1.5)	1
Diagnostic indication
Cancer	Reference	0
Benign neoplasm	0.9 (0.7–1.1)	−1
Diverticular disease	0.8 (0.7–1.0)	−2
Neoadjuvant chemotherapy with last dose within 90 days
No	Reference	0
Yes	1.6 (1.2–2.0)	4
Bowel Prep
Combined	Reference	0
No prep	2.3 (2.0–2.7)	8
Mechanical only	1.6 (1.4–1.9)	5
Oral antibiotic only	1.3 (1.0–1.8)	3
Missing	1.5 (1.2–1.8)	4
ASA class
I/II	Reference	0
III	1.4 (1.2–1.6)	3
IV	1.4 (1.0–2.0)	4
Approach with anastomosis location
Laparoscopic with colocolostomy	Reference	0
Robotic with colocolostomy	0.5 (0.3–0.7)	−8
Laparoscopic with coloproctostomy	1.0 (0.8–1.1)	−1
Open with coloproctostomy	1.0 (0.8–1.2)	0
Robotic with coloproctostomy	1.1 (0.9–1.5)	1
Open with colocolostomy	1.5 (1.3–1.8)	4
Operative time, minutes
≤ 122	Reference	0
123–168	1.1 (0.9–1.3)	1
169–225	1.3 (1.1–1.5)	3
≥ 226	1.6 (1.3–1.9)	4
Wound class
I/II	Reference	0
III/IV	1.5 (1.3–1.7)	4