Figure 2.

Global overview of antimicrobial resistance mutations. (A) Global distribution of quinolone resistance-determining region (QRDR) mutations. Countries are colored by the total percentage of sequences carrying QRDR mutations in the genome collection where n ≥ 20 sequences were available, as per inset legend. Unknown indicates countries where 0–19 sequences were available. Locations where sequences also carrying acrB-R717Q/L mutations have been isolated are indicated as labeled. (B) Distribution of QRDR mutations by genotype and region. Genotype/region combinations are included where ≥20 isolates have been sequenced from the region and ≥5% of those carry QRDR mutations. Genotypes also carrying acrB-R717Q/L mutations are labeled as per the inset legend.