FIG. 1.

PipMaker sequence alignments. (A) Sequence (15,522 bp) surrounding mouse Ndn was compared to sequence (20 kb) surrounding human NDN. (B) Twenty kilobases of sequence surrounding human NDN was compared to Ndn. The arrow and full-height box indicate the position of Ndn and NDN, with the open reading frame shaded black and the untranslated regions shaded gray. Half-height boxes outside Ndn and NDN indicate repetitive elements. Low boxes within Ndn and NDN indicate CpG-rich regions, within which white shading indicates a CpG/GpC ratio of ≥0.60 and gray shading indicates a CpG/GpC ratio of ≥0.75. On the plot below each sequence schematic, regions of homology are shown by black dashes and percent nucleotide identity is indicated on the right. See http://nog.cse.psu.edu/pipmaker/ for details of mouse and human repeat types. UTR, untranslated region; LTR, long terminal repeat.