Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structures of siderophore-β-lactam Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.
