Table 2.
Evaluation of gene regulatory networks in response to the GSE20635 adipose gene expression data.
| KEGG ID | Descriptor | Node | Edge | Light | Dark | ||
|---|---|---|---|---|---|---|---|
| P ‐value | FDR | P ‐value | FDR | ||||
| rno04340 | hedgehog signalling pathway | 22 | 40 | 2.89 × 10–6 | 0.0001 | 0.2773 | 0.8443 |
| rno05217 | basal cell carcinoma | 19 | 38 | 2.87 × 10–5 | 0.0007 | 0.2734 | 0.8443 |
| rno04710 | circadian rhythm – mammal | 13 | 58 | 0.0008 | 0.0072 | 0.0390 | 0.4951 |
| rno04950 | maturity onset diabetes of the young | 20 | 28 | 0.0369 | 0.2355 | 0.3360 | 0.8443 |
| rno04976 | nile secretion | 13 | 12 | 0.0446 | 0.2528 | 0.3514 | 0.8443 |
| rno05031 | amphetamine addiction | 13 | 28 | 0.0662 | 0.3188 | 0.0362 | 0.4951 |
| rno04115 | p53 signalling pathway | 32 | 31 | 0.0687 | 0.3187 | 0.0717 | 0.6097 |
| rno04960 | aldosterone‐regulated sodium reabsorption | 16 | 15 | 0.0981 | 0.4171 | 0.1387 | 0.7860 |
| rno04910 | insulin signalling pathway | 6 | 5 | 0.1233 | 0.4836 | 0.1959 | 0.8443 |
| rno05134 | legionellosis | 14 | 12 | 0.1988 | 0.6521 | 0.1951 | 0.8443 |
| rno05143 | African trypanosomiasis | 6 | 5 | 0.2133 | 0.6521 | 0.2385 | 0.8443 |
| rno04150 | mTOR signalling pathway | 6 | 5 | 0.2174 | 0.6521 | 0.3564 | 0.8443 |
| rno04961 | endocrine and other factor‐regulated calcium reabsorption | 6 | 7 | 0.2729 | 0.7212 | 0.8806 | 0.9166 |
| rno04350 | TGF‐beta signalling pathway | 20 | 26 | 0.2744 | 0.7212 | 0.3830 | 0.8443 |
| rno05030 | cocaine addiction | 16 | 22 | 0.2828 | 0.7212 | 0.2840 | 0.8443 |
| rno05218 | melanoma | 6 | 5 | 0.3131 | 0.7380 | 0.4150 | 0.8443 |
| rno04978 | mineral absorption | 6 | 5 | 0.3184 | 0.7380 | 0.9756 | 0.9756 |
| rno04920 | adipocytokine signalling pathway | 9 | 10 | 0.3618 | 0.7687 | 0.5896 | 0.8943 |
| rno05215 | prostate cancer | 9 | 7 | 0.3879 | 0.7908 | 0.5105 | 0.8443 |
| rno04962 | vasopressin‐regulated water reabsorption | 7 | 6 | 0.4031 | 0.7908 | 0.2313 | 0.8443 |
| rno05211 | renal cell carcinoma | 13 | 22 | 0.4369 | 0.8252 | 0.4897 | 0.8443 |
| rno05213 | endometrial cancer | 7 | 10 | 0.4564 | 0.8312 | 0.8180 | 0.9166 |
| rno05216 | thyroid cancer | 7 | 10 | 0.4754 | 0.8361 | 0.8243 | 0.9166 |
| rno04110 | cell cycle | 20 | 26 | 0.5110 | 0.8386 | 0.4408 | 0.8443 |
| rno05222 | small cell lung cancer | 25 | 38 | 0.5599 | 0.8386 | 0.8768 | 0.9166 |
| rno05221 | acute myeloid leukaemia | 12 | 10 | 0.5768 | 0.8386 | 0.4365 | 0.8443 |
| rno05212 | pancreatic cancer | 9 | 20 | 0.5774 | 0.8386 | 0.7734 | 0.9166 |
| rno05220 | chronic myeloid leukaemia | 5 | 3 | 0.5830 | 0.8386 | 0.9307 | 0.9493 |
| rno04620 | toll‐like receptor signalling pathway | 12 | 11 | 0.6032 | 0.8386 | 0.6339 | 0.9166 |
| rno05200 | pathways in cancer | 82 | 170 | 0.6136 | 0.8386 | 0.8633 | 0.9167 |
| rno05152 | tuberculosis | 42 | 163 | 0.6314 | 0.8386 | 0.7440 | 0.9166 |
| rno04310 | wnt signalling pathway | 13 | 40 | 0.6413 | 0.8386 | 0.7301 | 0.9166 |
| rno03320 | PPAR signalling pathway | 64 | 258 | 0.6763 | 0.8412 | 0.6592 | 0.9166 |
| rno04630 | Jak‐STAT signalling pathway | 25 | 90 | 0.7192 | 0.8506 | 0.7465 | 0.9166 |
| rno04210 | apoptosis | 8 | 12 | 0.7266 | 0.8506 | 0.7406 | 0.9166 |
| rno04510 | focal adhesion | 5 | 6 | 0.8867 | 0.9504 | 0.5178 | 0.8443 |
| rno04916 | melanogenesis | 15 | 14 | 0.9362 | 0.9504 | 0.5246 | 0.8443 |