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. 2015 Oct 1;9(5):204–215. doi: 10.1049/iet-syb.2014.0037

Fig. 1.

Fig. 1

Kinetic scheme of AA metabolism considered for mathematical modelling

Metabolic degradation of AA via COX and LOX pathway yields eicosanoids: PGs, thromboxane (TX), LTs and hydro(pero)xyeicosatetraenoic acids

Full lines with the corresponding enzymes depict the direction of metabolic fluxes, dotted lines depict either inhibitory or activating effects on enzymes

Numeration of the fluxes reflects the reaction rates of the mathematical model