Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Values of [PGE2]/[LTC4] ratio at rest and minimal values after dosing of 25 mg indomethacin (∼at t = 4 h) for all model populations in states of NI and I
| Condition | Model state | NA | ATA | AIA(1) | AIA(2) | AIA(3) |
|---|---|---|---|---|---|---|
| basal (without drug) | NI | 110.4 | 28.0 | 4.1 | 6.2 | 0.91 |
| I | 110.4 | 28.0 | 0.94 | 1.2 | 0.21 | |
| minimum after indomethacin (25 mg) | NI | 1.1 | 0.28 | 0.045 | 0.063 | 0.010 |
| I | 7.0 | 1.8 | 0.044 | 0.073 | 0.0099 |
