Table 2.
Details of independent test set
| PDB | First molecule | Second molecule | H | NH |
|---|---|---|---|---|
| 1cdl | calcium‐bound calmodulin | peptide of the kinase | 6 | 6 |
| 1dva | coagulation Factor VIIA | peptide exosite inhibitor E‐76 | 5 | 18 |
| 1dx5 | serine proteinase alpha‐thrombin | thrombomodulin | 3 | 13 |
| 1ebp | EPO receptor | EPO mimetics peptide 1 | 4 | 5 |
| 1es7 | bone morphogenetic protein‐2 | bone morphogenetic protein receptor IA | 1 | 3 |
| 1fak | soluble tissue factor | blood coagulation factor VIIa | 2 | 19 |
| 1fe8 | von willebrand factor | immunoglobulin IGG RU5 | 0 | 5 |
| 1foe | Rac1 | tiam1 protein | 1 | 1 |
| 1g3i | HslV protease | HslU ATPase | 5 | 0 |
| 1gl4 | nidogen‐1 | immunoglobulin‐like domain 3 of perlecan | 5 | 2 |
| 1ihb | p18INK4C | p18INK4C | 0 | 4 |
| 1jat | Mms2 | Ubc13 | 2 | 0 |
| 1jpp | beta‐catenin | adenomatous polyposis coli | 2 | 5 |
| 1mq8 | intercellular adhesion molecule‐1 | integrin alpha‐L | 1 | 0 |
| 2hhb | hemoglobin (alpha chain) | hemoglobin (beta chain) | 0 | 1 |
| 1nfi | NF‐KAPPA‐B | I‐KAPPA‐B‐ALPHA | 1 | 1 |
| 1nun | FGF10 | FGFR2b | 0 | 3 |
| 1ub4 | MazF protein | MazE protein | 0 | 1 |
H – hot spot; NH – non‐hot spot