TABLE 3.

Structural and metabolic brain network hub nodes in MCI and HC groups.

Hub nodes			BCi in structural networks			BCi in metabolic networks
			MCI	HC	p value	MCI	HC	p value
Common hub of three networks	MCI structural brain network and HC and MCI metabolic brain networks	INS.L	0.048	0.023	0.154	0.034	0.056	0.907
Common hub of two networks	HC and MCI structural brain networks	LING.L	0.035	0.081	0.018*	0.011	0.022	0.031▲
		MTG.R	0.036	0.047	0.427	0.011	0.011	0.367
		MOG.L	0.128	0.045	0.002*	0.011	0.011	0.382
	MCI structural and metabolic brain networks	PUT.R	0.034	0.023	0.018*	0.034	0.012	0.104
	HC metabolic and MCI structural brain networks	LING.R	0.035	0.012	0.019*	0.011	0.045	1.000
Unique hub	MCI structural brain network	STG.L	0.056	0.012	0.092	0.011	0.023	0.929
		STG.R	0.037	0.011	0.107	0.012	0.011	0.229
		MTG.L	0.036	0.011	0.179	0.011	0.012	0.514
	HC structural brain network	HIP.R	0.012	0.057	0*	0.011	0.011	0.217
		MFG.L	0.017	0.050	0.006*	0.015	0.011	0.851
	MCI metabolic brain network	ORBinf.L	0.012	0.011	0*	0.037	0.023	0.116
		OLF.R	0.012	0.011	0*	0.034	0.024	0.390
		PAL.L	0.012	0.011	0*	0.034	0.011	0.014▲
	HC metabolic brain network	CAL.R	0.012	0.023	0.011*	0.011	0.034	0.015▲
		ORBsup.L	0.012	0.023	0.183	0.014	0.030	0.014▲

The table summarizes all the hub nodes of the structural and metabolic brain networks in the MCI and HC groups.

*Significant difference between the structural networks in the HC and MCI groups (p < 0.05), ^▲Significant difference between the metabolic networks in the HC and MCI groups (p < 0.05).

MCI, mild cognitive impairment; HC, healthy controls; INS.L, left insula; LING.L, left lingual gyrus; MTG.R, right middle temporal gyrus; MOG.L, left middle occipital gyrus; PET.R, right putamen; LING.R, right lingual gyrus; STG.L, left superior temporal gyrus; STG.R, right superior temporal gyrus; MTG.L, left middle temporal gyrus; HIP.R, right hippocampus; MFG.L, left middle frontal gyrus; ORBinf.L, left orbital inferior frontal gyrus; OLF.R, right olfactory cortex; PAL.L, left globus pallidus; CAL.R, right calcarine fissure and surrounding cortex; ORBsup.L, left orbital superior frontal gyrus.