Fig 3. Observations of nAb ID50/ID80 titers against days since SARS-CoV-2 diagnosis from V1 (n = 329) and V2 (n = 186) stratified by COVID-19 severity (n = 65 for V1 and n = 32 for V2 in asymptomatic, n = 132 for V1 and n = 87 for V2 in symptomatic outpatient, and n = 132 for V1 and n = 67 for V2 in hospitalized).

Geometric means (red lines) and 95% confidence bands (pink ribbons) stratified by COVID-19 severity were estimated using GAM with mixed effect to account for the correlations between visits within participants. COVID-19, Coronavirus Disease 2019; GAM, generalized additive model; nAb, neutralizing antibody; SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2.