Table 8. Summary table illustrating SNPs with significant associations with GDM, according to race.
| Filipino | Japanese | PI | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | SNP | OR | P_value | OR | P_value | OR | P_value | |||||||
| Dominant | EXT2(*) | rs1113132 | 1.53 | ( | 0.034 | ) | ||||||||
| HHEX(*) | rs1111875 | 1.60 | ( | 0.027 | ) | |||||||||
| IGFBP2(*) | rs4402960 | 0.32 | ( | 0.003 | ) | |||||||||
| KCNQ1(*)(**) | rs2237892 | 0.5 | ( | < .001 | ) | 0.45 | ( | 0.035 | ) | |||||
| MTNR 1B (*)(***) | rs10830963 | 0.62 | ( | 0.028 | ) | 0.42 | ( | 0.021 | ) | |||||
| SLC30A8(*)(***) | rs13266634 | 0.56 | ( | 0.006 | ) | |||||||||
| Recessive | KCNQ1(*) | rs2237892 | 0.51 | ( | 0.019 | ) | ||||||||
| KCNQ1(*) | rs2237895 | 1.84 | ( | 0.046 | ) | |||||||||
| MTNR 1B(*)(***) | rs10830963 | 0.37 | ( | < .001 | ) | |||||||||
| SLC30A8(*)(**) | rs13266634 | 2.43 | ( | 0.03 | ) | |||||||||
The table lists SNPs that showed significant unadjusted OR p values (p<0.05; *), significant Breslow-Day test p values (p<0.05; **) or values from Mantel-Haenszel formula significantly different from 1.0 (***) in the Dominant (Table 3) and Recessive (Table 4) models. Significance was determined after multivariable logistic regression analysis was performed to control for confounding factors.