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mRNA levels of TNF–α, NF–kB, IL–1β, IL–6 and Klotho in mice brain. Compared with normal group, #: p < 0.05, ##: p < 0.01; Compared with D–gal group, *: p < 0.05, **: p < 0.01. NC: normal control group; D–gal: D–gal model group; SL: low–dose SDE group; SM: medium–dose SDE group; SL: high–dose SDE group; Vc: Vc positive control group.
