Table 2.

Mixed-effects model summary to predict worst pain in the entire year.

Effect	Estimate	P
Intercept	8.9	<0.0001
Age (per year)	−0.01	0.24
Gender
Female	Ref
Male	−0.76	0.0005
Opioid
Morphine	Ref
Methadone	−1.24	0.0014
Pain classification
Nociceptive	Ref
Neuropathic	+0.41	0.14
Mixed	+0.63	0.015
Nociplastic	+1.88	<0.0001
Missing data	+1.16	<0.28
Random effects (time, id*)	—	<0.0001

^*id: subject. Generalized additive model with integrated smoothness estimation.